Melatonin reduces the mortality of severely-infected COVID-19 patients

  • Dun-Xian Tan UT Health San Antonio, Long School of Medicine, San Antonio, TX, USA
  • Russel J Reiter UT Health San Antonio, Long School of Medicine, San Antonio, TX, USA
Keywords: melatonin, COVID-19, severe COVID-19 patients, mortality, immune tolerance

Abstract

SARS-CoV-2 has ravaged the population of the world for two years. Scientists have not yet identified an effective therapy to reduce the mortality of severe COVID-19 patients. In a single-center, open-label, randomized clinical trial, it was observed that melatonin treatment lowered the mortality rate by 93% in severely-infected COVID-19 patients compared with the control group (see below). This is seemingly the first report to show such a huge mortality reduction in severe COVID-19 infected individuals with a simple treatment. If this observation is confirmed by more rigorous clinical trials, melatonin could become an important weapon to combat this pandemic.


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Published
2021-12-31
How to Cite
[1]
Tan, D.-X. and Reiter, R.J. 2021. Melatonin reduces the mortality of severely-infected COVID-19 patients. Melatonin Research. 4, 4 (Dec. 2021), 613-616. DOI:https://doi.org/https://doi.org/10.32794/mr112500115.